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Approved Drugs
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Inhibitors
Name:  1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C22H22N6O3
Similarity:  1.0
Relative Targets:   Fibroblast growth factor receptor 2  | Tyrosine-protein kinase BTK  |
Name:  1-[(3R)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C22H22N6O3
Similarity:  1.0
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]azetidin-1-yl]prop-2-en-1-one
Formula:  C21H20N6O3
Similarity:  0.8901098901098901
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[4-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula:  C23H24N6O3
Similarity:  0.8842105263157894
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  (E)-1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]-4-(dimethylamino)but-2-en-1-one
Formula:  C25H29N7O3
Similarity:  0.7980769230769231
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[(3S)-3-[4-amino-3-(3,5-dimethoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C20H22N6O3
Similarity:  0.7708333333333334
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[3-[[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]methyl]azetidin-1-yl]prop-2-en-1-one
Formula:  C22H22N6O3
Similarity:  0.75
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C22H26N6O3
Similarity:  0.7254901960784313
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  4-amino-N-(3,5-dimethoxyphenyl)-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrazolo[3,4-d]pyrimidine-3-carboxamide
Formula:  C21H23N7O4
Similarity:  0.7115384615384616
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  (E)-1-[3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]azetidin-1-yl]-4-(dimethylamino)but-2-en-1-one
Formula:  C24H27N7O3
Similarity:  0.7102803738317757
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[3-[4-amino-5-(3,5-dimethoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C21H23N5O3
Similarity:  0.6666666666666666
Relative Targets:   Fibroblast growth factor receptor 1  | Fibroblast growth factor receptor 4  |
Name:  N-[2-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]prop-2-enamide
Formula:  C20H20N6O3
Similarity:  0.6346153846153846
Relative Targets:   Fibroblast growth factor receptor 2  |
Name:  1-[3-[4-amino-5-(5,7-dimethoxybenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula:  C23H23N5O3S
Similarity:  0.5565217391304348
Relative Targets:   Fibroblast growth factor receptor 1  | Fibroblast growth factor receptor 4  |
Name:  1-[(3R)-3-(4-amino-3-ethynyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula:  C15H16N6O
Similarity:  0.5306122448979592
Relative Targets:   Dual specificity mitogen-activated protein kinase kinase 7  | Epidermal growth factor receptor  |