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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6134453781512605

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  1.0

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₆H₂₉ClFN₅O₃

Similarity:  0.8598130841121495

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₂

Similarity:  0.8113207547169812

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₂

Similarity:  0.8113207547169812

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₃S

Similarity:  0.8113207547169812

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₉ClFN₅O₃

Similarity:  0.7964601769911505

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₆H₂₇N₅O₂

Similarity:  0.7685185185185185

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₂H₂₂ClFN₆O

Similarity:  0.7619047619047619

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₂H₂₁ClFN₅O₂

Similarity:  0.7102803738317757

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₅H₂₇ClFN₅O₄S

Similarity:  0.7033898305084746

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[cyclopropyl(methyl)amino]but-2-enamide

Formula:  C₂₃H₂₃ClFN₅O₂

Similarity:  0.6972477064220184

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₂

Similarity:  0.6902654867256637

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₉N₅O₂

Similarity:  0.6869565217391305

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₁₈H₁₄ClFN₄O₂

Similarity:  0.68

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.6695652173913044

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.6695652173913044

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₃₀H₃₁N₅O₃

Similarity:  0.6693548387096774

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(4-oxo-1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₇ClFN₅O₄

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₆H₂₇ClFN₅O₄S

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-[(3,3-difluorocyclobutyl)amino]but-2-enamide

Formula:  C₂₃H₂₁ClF₃N₅O₂

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |