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Approved Drugs
Name: Futibatinib
Formula: C22H22N6O3
Similarity: 0.7708333333333334
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.5344827586206896
Inhibitors
Name: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H22N6O3
Similarity: 0.7708333333333334
Relative Targets: Fibroblast growth factor receptor 2 | Tyrosine-protein kinase BTK |
Name: 1-[(3R)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H22N6O3
Similarity: 0.7708333333333334
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H26N6O3
Similarity: 0.7708333333333334
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[3-[4-amino-5-(3,5-dimethoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H23N5O3
Similarity: 0.7634408602150538
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 4-amino-N-(3,5-dimethoxyphenyl)-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrazolo[3,4-d]pyrimidine-3-carboxamide
Formula: C21H23N7O4
Similarity: 0.7551020408163265
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[4-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H24N6O3
Similarity: 0.6796116504854369
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]azetidin-1-yl]prop-2-en-1-one
Formula: C21H20N6O3
Similarity: 0.6767676767676768
Relative Targets: Fibroblast growth factor receptor 2 |
Name: (E)-1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]-4-(dimethylamino)but-2-en-1-one
Formula: C25H29N7O3
Similarity: 0.6160714285714286
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3R)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.5961538461538461
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3S)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.5961538461538461
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3R)-3-[4-amino-3-(3-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.59
Relative Targets: Epidermal growth factor receptor |
Name: 1-[3-[4-amino-5-(5,7-dimethoxybenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C23H23N5O3S
Similarity: 0.5871559633027523
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[3-[[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]methyl]azetidin-1-yl]prop-2-en-1-one
Formula: C22H22N6O3
Similarity: 0.5794392523364486
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C24H22N6O2
Similarity: 0.5765765765765766
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[4-amino-3-(4-fluorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H19FN6O
Similarity: 0.5742574257425742
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O2
Similarity: 0.5742574257425742
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.57
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C20H20N8O
Similarity: 0.5660377358490566
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-[1-(4-methoxyphenyl)triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C22H23N9O2
Similarity: 0.5526315789473685
Relative Targets: Dual specificity mitogen-activated protein kinase kinase 7 |