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Approved Drugs
Name: Ibrutinib
Formula: C25H24N6O2
Similarity: 0.5
Inhibitors
Name: 1-[3-[4-amino-5-(3-quinolyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H20N6O
Similarity: 1.0
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3R)-3-[4-amino-5-(3-quinolyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H20N6O
Similarity: 1.0
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3R)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.7684210526315789
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[(3S)-3-[4-amino-3-(3-quinolyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N7O
Similarity: 0.7684210526315789
Relative Targets: Fibroblast growth factor receptor 2 |
Name: 1-[3-[4-amino-5-(benzofuran-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H19N5O2
Similarity: 0.7368421052631579
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[3-[4-amino-5-(7-methylbenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H21N5OS
Similarity: 0.6534653465346535
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[3-[4-amino-5-(benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]azetidin-1-yl]prop-2-en-1-one
Formula: C20H17N5OS
Similarity: 0.6428571428571429
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[3-[4-amino-5-(7-methoxybenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C22H21N5O2S
Similarity: 0.6346153846153846
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3R)-3-[4-amino-3-(2-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.5981308411214953
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[3-[4-amino-5-(3,5-dimethoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C21H23N5O3
Similarity: 0.5961538461538461
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3R)-3-[4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C23H22N6O
Similarity: 0.5688073394495413
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[3-[4-amino-5-(7-methoxybenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]azetidin-1-yl]prop-2-en-1-one
Formula: C21H19N5O2S
Similarity: 0.5514018691588785
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[3-[4-amino-5-(7-methoxy-5-methyl-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C23H23N5O2S
Similarity: 0.5495495495495496
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3R)-3-[4-amino-5-(7-methoxy-5-methyl-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C23H23N5O2S
Similarity: 0.5495495495495496
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3S)-3-[4-amino-5-(7-methoxy-5-methyl-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C23H23N5O2S
Similarity: 0.5495495495495496
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]prop-2-en-1-one
Formula: C19H20N6O
Similarity: 0.5436893203883495
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |
Name: 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C24H22N6O2
Similarity: 0.5391304347826087
Relative Targets: Epidermal growth factor receptor |
Name: 1-[3-[4-amino-5-(5,7-dimethoxybenzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C23H23N5O3S
Similarity: 0.5350877192982456
Relative Targets: Fibroblast growth factor receptor 1 | Fibroblast growth factor receptor 4 |
Name: 1-[(3R)-3-[4-amino-3-(1-methylindol-3-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one
Formula: C22H23N7O
Similarity: 0.5315315315315315
Relative Targets: Epidermal growth factor receptor | Mitogen-activated protein kinase kinase 7 |