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Approved Drugs

Name:  Futibatinib

Formula:  C22H22N6O3

Similarity:  0.7980769230769231

Inhibitors

Name:  (E)-1-[3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]azetidin-1-yl]-4-(dimethylamino)but-2-en-1-one

Formula:  C24H27N7O3

Similarity:  0.9019607843137255

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C22H22N6O3

Similarity:  0.7980769230769231

Relative Targets:   Fibroblast growth factor receptor 2  | Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C22H22N6O3

Similarity:  0.7980769230769231

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[4-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]prop-2-en-1-one

Formula:  C23H24N6O3

Similarity:  0.7117117117117117

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]azetidin-1-yl]prop-2-en-1-one

Formula:  C21H20N6O3

Similarity:  0.7102803738317757

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[3-[[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]methyl]azetidin-1-yl]prop-2-en-1-one

Formula:  C22H22N6O3

Similarity:  0.6173913043478261

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[(3S)-3-[4-amino-3-(3,5-dimethoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C20H22N6O3

Similarity:  0.6160714285714286

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C22H26N6O3

Similarity:  0.5982905982905983

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  4-amino-N-(3,5-dimethoxyphenyl)-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrazolo[3,4-d]pyrimidine-3-carboxamide

Formula:  C21H23N7O4

Similarity:  0.575

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  N-[2-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]prop-2-enamide

Formula:  C20H20N6O3

Similarity:  0.5470085470085471

Relative Targets:   Fibroblast growth factor receptor 2  |

Name:  (E)-1-[3-[4-amino-5-(7-methoxy-5-methyl-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]-4-(dimethylamino)but-2-en-1-one

Formula:  C26H30N6O2S

Similarity:  0.5348837209302325

Relative Targets:   Fibroblast growth factor receptor 1  | Fibroblast growth factor receptor 4  |

Name:  1-[3-[4-amino-5-(3,5-dimethoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C21H23N5O3

Similarity:  0.5338983050847458

Relative Targets:   Fibroblast growth factor receptor 1  | Fibroblast growth factor receptor 4  |

Name:  (E)-1-[(3R)-3-(4-amino-3-phenyl-pyrazolo[3,4-d]pyrimidin-1-yl)-1-piperidyl]-4-(dimethylamino)but-2-en-1-one

Formula:  C22H27N7O

Similarity:  0.5163934426229508

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-1-[(3R)-3-[4-amino-3-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-4-(dimethylamino)but-2-en-1-one

Formula:  C23H26F3N7O

Similarity:  0.5038759689922481

Relative Targets:   Epidermal growth factor receptor  | Mitogen-activated protein kinase kinase 7  |