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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.5564516129032258

Inhibitors

Name:  (7S)-2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  1.0

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  1.0

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.8775510204081632

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-chloro-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28ClN5O4

Similarity:  0.8775510204081632

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.8775510204081632

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7R)-2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.8775510204081632

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trimethoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O5

Similarity:  0.87

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-ethyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H33N5O4

Similarity:  0.87

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-isopropyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H35N5O4

Similarity:  0.8529411764705882

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-propyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H35N5O4

Similarity:  0.8446601941747572

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[3,5-dimethoxy-4-(1-methylcyclopropyl)phenyl]-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H35N5O4

Similarity:  0.8285714285714286

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-cyclopropyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H33N5O4

Similarity:  0.8269230769230769

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(4-cyclopropyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H33N5O4

Similarity:  0.8269230769230769

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7R)-2-(4-cyclopropyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H33N5O4

Similarity:  0.8269230769230769

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-but-2-ynoyl-4-piperidyl)-2-(3,5-dimethoxy-4-methyl-phenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H31N5O4

Similarity:  0.8155339805825242

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-cyclopentyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H37N5O4

Similarity:  0.7747747747747747

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3-chloro-5-methoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H25BrClN5O3

Similarity:  0.7745098039215687

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trimethylphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O2

Similarity:  0.7623762376237624

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxy-3-methyl-benzothiophen-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H29N5O3S

Similarity:  0.7570093457943925

Relative Targets:   Tyrosine-protein kinase BTK  |