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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.5714285714285714

Inhibitors

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trichlorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C21H22Cl3N5O2

Similarity:  0.8695652173913043

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3-chloro-5-methoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H25BrClN5O3

Similarity:  0.8421052631578947

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3-chloro-5-ethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H27BrClN5O3

Similarity:  0.8163265306122449

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.7281553398058253

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.7281553398058253

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7R)-2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.7281553398058253

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trimethylphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O2

Similarity:  0.72

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-chloro-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28ClN5O4

Similarity:  0.7115384615384616

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  0.6792452830188679

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  0.6792452830188679

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  (7R)-2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  0.6792452830188679

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxybenzofuran-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H27N5O4

Similarity:  0.6666666666666666

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxybenzothiophen-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H27N5O3S

Similarity:  0.6666666666666666

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trimethoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O5

Similarity:  0.6605504587155964

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-ethyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H33N5O4

Similarity:  0.6605504587155964

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxy-3-methyl-benzothiophen-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H29N5O3S

Similarity:  0.6545454545454545

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxy-1-methyl-indol-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H30N6O3

Similarity:  0.6545454545454545

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-isopropyl-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C26H35N5O4

Similarity:  0.6486486486486487

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(5-methoxychroman-7-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H31N5O4

Similarity:  0.6486486486486487

Relative Targets:   Tyrosine-protein kinase BTK  |