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Approved Drugs

Name:  Zanubrutinib

Formula:  C27H29N5O3

Similarity:  0.8053097345132744

Inhibitors

Name:  2-(3-chloro-4-phenoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H28ClN5O3

Similarity:  0.8899082568807339

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(3-methoxy-4-phenoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H31N5O4

Similarity:  0.8660714285714286

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.8053097345132744

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(4-phenoxyphenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H29N5O3

Similarity:  0.8053097345132744

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(3,5-dimethoxy-4-phenoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C29H33N5O5

Similarity:  0.7258064516129032

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[4-(2,4-difluorophenoxy)phenyl]-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C27H27F2N5O3

Similarity:  0.71900826446281

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-phenoxyphenyl)-7-(1-prop-2-enoylazetidin-3-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H25N5O3

Similarity:  0.6694915254237288

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (7S)-7-(1-but-2-ynoyl-4-piperidyl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C28H29N5O3

Similarity:  0.6693548387096774

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxybenzofuran-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H27N5O4

Similarity:  0.6147540983606558

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxybenzothiophen-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H27N5O3S

Similarity:  0.6147540983606558

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-methoxy-1-methyl-indol-6-yl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C25H30N6O3

Similarity:  0.6048387096774194

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3-chloro-5-methoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C22H25BrClN5O3

Similarity:  0.6

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trimethylphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O2

Similarity:  0.5882352941176471

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-(1-prop-2-enoyl-4-piperidyl)-2-(3,4,5-trichlorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C21H22Cl3N5O2

Similarity:  0.5882352941176471

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3,5-dichloro-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C21H22BrCl2N5O2

Similarity:  0.5882352941176471

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  (7S)-2-(3,5-dimethoxy-4-methyl-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C24H31N5O4

Similarity:  0.5853658536585366

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3-chloro-5-ethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H27BrClN5O3

Similarity:  0.5853658536585366

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-(4-bromo-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28BrN5O4

Similarity:  0.5853658536585366

Relative Targets:   Tyrosine-protein kinase BTK  | Tyrosine-protein kinase BTK  |

Name:  2-(4-chloro-3,5-dimethoxy-phenyl)-7-(1-prop-2-enoyl-4-piperidyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

Formula:  C23H28ClN5O4

Similarity:  0.5853658536585366

Relative Targets:   Tyrosine-protein kinase BTK  |