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Approved Drugs

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Inhibitors

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.8269230769230769

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H32ClN5O3

Similarity:  0.6896551724137931

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H28ClFN6O2

Similarity:  0.6551724137931034

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.628099173553719

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.628099173553719

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C33H38N10O2

Similarity:  0.5793103448275863

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C24H27N5O3S

Similarity:  0.5725806451612904

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]propan-1-one

Formula:  C25H32N6O2S

Similarity:  0.5390625

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  0.5202702702702703

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.5190839694656488

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29FN6O2S

Similarity:  0.5190839694656488

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H33N7O3

Similarity:  0.5074626865671642

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C26H32N6O3S

Similarity:  0.5074626865671642

Relative Targets:   Epidermal growth factor receptor  |