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Name:  Olmutinib

Formula:  C₂₆H₂₆N₆O₂S

Similarity:  0.5075757575757576

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.8148148148148148

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-(2-methoxy-4-morpholino-anilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29N5O4S

Similarity:  0.7767857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]propan-1-one

Formula:  C25H32N6O2S

Similarity:  0.6896551724137931

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29FN6O2S

Similarity:  0.65

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.6439393939393939

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.6439393939393939

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C26H32N6O3S

Similarity:  0.6341463414634146

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.6333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₂₉H₃₃N₉O₃

Similarity:  0.631578947368421

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.631578947368421

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C27H32N6O4S

Similarity:  0.609375

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[(1-methylpyrazol-4-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.6055045871559633

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.6016949152542372

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[(1-methylpyrazol-3-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.5909090909090909

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C24H31ClN6O3

Similarity:  0.5725806451612904

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[(3R)-3-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₂₉H₃₃N₉O₃

Similarity:  0.5390070921985816

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  Olmutinib

Formula:  C₂₆H₂₆N₆O₂S

Similarity:  0.5075757575757576

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.5033557046979866

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.5

Relative Targets:   Epidermal growth factor receptor  |