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Inhibitors

Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C26H32N6O3S

Similarity:  0.868421052631579

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C27H33N7O4

Similarity:  0.8016528925619835

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-(2-methoxy-4-morpholino-anilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29N5O4S

Similarity:  0.788135593220339

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H33N7O3

Similarity:  0.6904761904761905

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.6774193548387096

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29FN6O2S

Similarity:  0.6535433070866141

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C24H27N5O3S

Similarity:  0.609375

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]propan-1-one

Formula:  C25H32N6O2S

Similarity:  0.5877862595419847

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-(1-prop-2-enoyl-4-piperidyl)pteridin-7-one

Formula:  C26H32N8O3

Similarity:  0.5579710144927537

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C31H36N10O3

Similarity:  0.5526315789473685

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[2-[(1-methylpyrazol-3-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.5454545454545454

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-(1-prop-2-enoyl-4-piperidyl)pyrido[2,3-d]pyrimidin-7-one

Formula:  C28H35N7O3

Similarity:  0.5390070921985816

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[(1-methylpyrazol-4-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.5327868852459017

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.5294117647058824

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.5227272727272727

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.5142857142857142

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.5142857142857142

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.5107913669064749

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoyl-3-piperidyl]pteridin-7-one

Formula:  C26H32N8O3

Similarity:  0.5034965034965035

Relative Targets:   Tyrosine-protein kinase BTK  |