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Approved Drugs

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Inhibitors

Name:  1-[(3R)-3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C18H21N7O2

Similarity:  0.7333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[(1-methylpyrazol-4-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.7333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.6238532110091743

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.6126126126126126

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[(3R,4R)-3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C19H20F3N7O2

Similarity:  0.6019417475728155

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H33N7O3

Similarity:  0.5689655172413793

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[(3R)-3-[[5-Chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C18H20ClN7O2

Similarity:  0.5643564356435643

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[(1-methylpyrazol-3-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C18H20N6O2S

Similarity:  0.56

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H35N7O3

Similarity:  0.5517241379310345

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[(3R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C17H19ClN8O

Similarity:  0.5346534653465347

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C27H33N7O4

Similarity:  0.5327868852459017

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.5142857142857142

Relative Targets:   Epidermal growth factor receptor  |