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Approved Drugs
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Inhibitors
Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C25H30FN7O2
Similarity:  0.8018018018018018
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C25H30N6O2S
Similarity:  0.7837837837837838
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C26H33N7O3
Similarity:  0.7807017543859649
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C23H29ClN6O2
Similarity:  0.7522935779816514
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C27H33N7O4
Similarity:  0.6774193548387096
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]propan-1-one
Formula:  C25H32N6O2S
Similarity:  0.6638655462184874
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C24H27N5O3S
Similarity:  0.6333333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[5-chloro-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C24H31ClN6O3
Similarity:  0.628099173553719
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C25H29FN6O2S
Similarity:  0.6260162601626016
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[[2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C18H21N7O2
Similarity:  0.6238532110091743
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C26H32N6O3S
Similarity:  0.6111111111111112
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]amino]-1-piperidyl]prop-2-en-1-one
Formula:  C24H31N9O
Similarity:  0.6097560975609756
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[5-chloro-2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula:  C23H28ClFN6O2
Similarity:  0.6083333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C31H36N10O3
Similarity:  0.6028368794326241
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.5952380952380952
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.5952380952380952
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |
Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C30H34N8O3
Similarity:  0.5869565217391305
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C30H34N8O3
Similarity:  0.5869565217391305
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |
Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula:  C33H38N10O2
Similarity:  0.5862068965517241
Relative Targets:   Tyrosine-protein kinase ITK/TSK  |