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Approved Drugs

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Inhibitors

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C27H33N7O4

Similarity:  0.868421052631579

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C26H32N6O3S

Similarity:  0.7931034482758621

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.7807017543859649

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.7521367521367521

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C27H32N6O4S

Similarity:  0.6904761904761905

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H35N7O3

Similarity:  0.648

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-(2-methoxy-4-morpholino-anilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29N5O4S

Similarity:  0.648

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-(1-prop-2-enoyl-4-piperidyl)pyrido[2,3-d]pyrimidin-7-one

Formula:  C28H35N7O3

Similarity:  0.6183206106870229

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-(1-prop-2-enoyl-4-piperidyl)pteridin-7-one

Formula:  C26H32N8O3

Similarity:  0.6153846153846154

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.6111111111111112

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.6065573770491803

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H29FN6O2S

Similarity:  0.5891472868217055

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pyrido[2,3-d]pyrimidin-7-one

Formula:  C27H33N7O3

Similarity:  0.5714285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrido[2,3-d]pyrimidin-7-one

Formula:  C27H33N7O3

Similarity:  0.5714285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C18H21N7O2

Similarity:  0.5689655172413793

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.5681818181818182

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.5681818181818182

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C26H34N8O3

Similarity:  0.5597014925373134

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H28ClFN6O2

Similarity:  0.5590551181102362

Relative Targets:   Epidermal growth factor receptor  |