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Inhibitors

Name:  N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.87

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.7314814814814815

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.6846846846846847

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.64

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.6299212598425197

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H32N6O3

Similarity:  0.6299212598425197

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H31N7O4

Similarity:  0.6060606060606061

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C21H19N7O2

Similarity:  0.5877192982456141

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.5789473684210527

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.5703703703703704

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.5702479338842975

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.5538461538461539

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C22H21N7O3

Similarity:  0.5454545454545454

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.5111111111111111

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[[1-(1-methyl-4-piperidyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.5075757575757576

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.5035971223021583

Relative Targets:   Tyrosine-protein kinase JAK3  |