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Name:  N-[3-[[2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C22H21N7O3

Similarity:  0.87

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C21H19N7O2

Similarity:  0.81

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(1-methyl-4-piperidyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.6864406779661016

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C₂₀H₂₂ClN₇O₂

Similarity:  0.6605504587155964

Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.6548672566371682

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C₁₉H₂₀N₆O₂

Similarity:  0.6320754716981132

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.5905511811023622

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.5891472868217055

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C₁₉H₂₀N₆O₂

Similarity:  0.5727272727272728

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]but-2-enamide

Formula:  C25H23N5O3

Similarity:  0.5702479338842975

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.5681818181818182

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H32N6O3

Similarity:  0.5681818181818182

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₄H₂₆N₈O₂

Similarity:  0.5655737704918032

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[[5-Chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C₁₉H₂₀ClN₇O₂

Similarity:  0.5614035087719298

Relative Targets:   Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[7-(2-methoxyethyl)-2-[(6-methoxy-3-pyridyl)amino]-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C₂₃H₂₃N₇O₄

Similarity:  0.5609756097560976

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C₁₉H₂₀N₆O₂

Similarity:  0.5585585585585585

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.5583333333333333

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.5555555555555556

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H31N7O4

Similarity:  0.5474452554744526

Relative Targets:   Tyrosine-protein kinase JAK3  |