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Inhibitors

Name:  N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.711864406779661

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.7109375

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.6691729323308271

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H32N6O3

Similarity:  0.6691729323308271

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-5-isopropyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C30H36N8O4

Similarity:  0.6496350364963503

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H31N7O4

Similarity:  0.644927536231884

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]but-2-enamide

Formula:  C25H23N5O3

Similarity:  0.64

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C26H32N8O3

Similarity:  0.6335877862595419

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.6187050359712231

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.616

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.6099290780141844

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.5891472868217055

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  Egfr-IN-1

Formula:  C28H30N6O4

Similarity:  0.583941605839416

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C21H19N7O2

Similarity:  0.5806451612903226

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C22H21N7O3

Similarity:  0.5658914728682171

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.5658914728682171

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.5555555555555556

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.5547945205479452

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-5-propyl-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C32H37N7O3

Similarity:  0.5540540540540541

Relative Targets:   Tyrosine-protein kinase JAK3  |