Searching results

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H31N7O3

Similarity:  0.8770491803278688

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.7984496124031008

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.7862595419847328

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₈H₂₉N₇O₃

Similarity:  0.7384615384615385

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H33N7O3

Similarity:  0.7238805970149254

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H32N6O3

Similarity:  0.7218045112781954

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.708029197080292

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.696969696969697

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-5-propyl-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C32H37N7O3

Similarity:  0.6928571428571428

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-cyclopropyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C32H35N7O3

Similarity:  0.6928571428571428

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(2-methoxyanilino)-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C24H21N5O3

Similarity:  0.672

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  Rociletinib

Formula:  C₂₇H₂₈F₃N₇O₃

Similarity:  0.6474820143884892

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C₂₇H₂₇F₃N₆O₄

Similarity:  0.6474820143884892

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.644927536231884

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₇H₂₈N₈O₃

Similarity:  0.6376811594202898

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₉H₃₁N₇O₃

Similarity:  0.6285714285714286

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₉H₃₂N₈O₄

Similarity:  0.6180555555555556

Relative Targets:   Epidermal growth factor receptor  |

Name:  Jak3-IN-1

Formula:  C₂₆H₃₀ClN₇O₂

Similarity:  0.6176470588235294

Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C₂₇H₂₈N₈O₄

Similarity:  0.6170212765957447

Relative Targets:   Epidermal growth factor receptor  |