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Inhibitors

Name:  (Z)-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C29H28FN7O2

Similarity:  1.0

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]azetidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C28H26FN7O2

Similarity:  0.9380530973451328

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (Z)-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4,4-dimethyl-pent-2-enenitrile

Formula:  C30H30FN7O2

Similarity:  0.8512396694214877

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (Z)-4-amino-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C29H29FN8O2

Similarity:  0.8512396694214877

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(2S)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4-methyl-4-morpholino-pent-2-enenitrile

Formula:  C29H26FN7O2

Similarity:  0.8278688524590164

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3S)-3-[4-amino-3-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile

Formula:  C29H26FN7O2

Similarity:  0.8278688524590164

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile

Formula:  C29H26FN7O2

Similarity:  0.8278688524590164

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[3-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]azetidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C28H26FN7O2

Similarity:  0.8166666666666667

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3S)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C29H28FN7O2

Similarity:  0.776

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C29H28FN7O2

Similarity:  0.776

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3S)-3-[4-amino-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile

Formula:  C33H35FN8O3

Similarity:  0.762962962962963

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-2-[(3S)-3-[4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile

Formula:  C33H35FN8O3

Similarity:  0.7518248175182481

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-2-[(2R)-2-[[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4-methyl-4-morpholino-pent-2-enenitrile

Formula:  C33H35FN8O3

Similarity:  0.7518248175182481

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-N-[(1S)-2-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-methyl-ethyl]-2-cyano-4-methyl-pent-2-enamide

Formula:  C27H26FN7O2

Similarity:  0.72

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-N-[(1R)-2-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-methyl-ethyl]-2-cyano-4-methyl-pent-2-enamide

Formula:  C27H26FN7O2

Similarity:  0.72

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethyl-pent-2-enenitrile

Formula:  C30H30FN7O2

Similarity:  0.6592592592592592

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-4-amino-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-pent-2-enenitrile

Formula:  C29H29FN8O2

Similarity:  0.6592592592592592

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-5-hydroxy-4,4-dimethyl-pent-2-enenitrile

Formula:  C30H30FN7O3

Similarity:  0.656934306569343

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-3-cyclopropyl-prop-2-enenitrile

Formula:  C29H26FN7O2

Similarity:  0.6397058823529411

Relative Targets:   Tyrosine-protein kinase BTK  |