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Inhibitors

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.9

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pteridin-7-one

Formula:  C25H30N8O3

Similarity:  0.9

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-prop-2-enoyl-3-piperidyl]pteridin-7-one

Formula:  C26H32N8O3

Similarity:  0.8596491228070176

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-prop-2-enoyl-3-piperidyl]pteridin-7-one

Formula:  C26H32N8O3

Similarity:  0.8596491228070176

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-(1-prop-2-enoyl-4-piperidyl)pyrido[2,3-d]pyrimidin-7-one

Formula:  C28H35N7O3

Similarity:  0.8135593220338984

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]pyrido[2,3-d]pyrimidin-7-one

Formula:  C27H33N7O3

Similarity:  0.7295081967213115

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]pyrido[2,3-d]pyrimidin-7-one

Formula:  C27H33N7O3

Similarity:  0.7295081967213115

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C26H34N8O3

Similarity:  0.6614173228346457

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-8-[(1-prop-2-enoylpyrrolidin-3-yl)methyl]pyrido[2,3-d]pyrimidin-7-one

Formula:  C28H35N7O3

Similarity:  0.6589147286821705

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C28H38N8O3

Similarity:  0.6363636363636364

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-(1-prop-2-enoyl-4-piperidyl)-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C33H40N8O3

Similarity:  0.6293706293706294

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C26H32N6O3S

Similarity:  0.627906976744186

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C26H33N7O3

Similarity:  0.6153846153846154

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-cyclopentyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C30H40N8O3

Similarity:  0.6115107913669064

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6044776119402985

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C27H28N8O3

Similarity:  0.6044776119402985

Relative Targets:   Epidermal growth factor receptor  |

Name:  7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-phenyl-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H36N8O3

Similarity:  0.5985915492957746

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-cyclohexyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3S)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C31H42N8O3

Similarity:  0.5985915492957746

Relative Targets:   Epidermal growth factor receptor  |

Name:  3-benzyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-1-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]-4H-pyrimido[4,5-d]pyrimidin-2-one

Formula:  C32H38N8O3

Similarity:  0.5862068965517241

Relative Targets:   Epidermal growth factor receptor  |