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Approved Drugs

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Inhibitors

Name:  N-methyl-2-[[2-[4-[4-[(2S)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.8473282442748091

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.8473282442748091

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.8473282442748091

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C28H29F3N8O3

Similarity:  0.7910447761194029

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H31ClN8O3

Similarity:  0.7153284671532847

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C27H29ClN8O3

Similarity:  0.6642857142857143

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[3-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H31ClN8O3

Similarity:  0.6503496503496503

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[4-(prop-2-enoylamino)butanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C29H33ClN8O3

Similarity:  0.636986301369863

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[5-(prop-2-enoylamino)pentanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C30H35ClN8O3

Similarity:  0.6241610738255033

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazine-1-carbonyl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H29ClN8O4

Similarity:  0.5555555555555556

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[3-(prop-2-enoylamino)propanoyl]piperazine-1-carbonyl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C29H31ClN8O4

Similarity:  0.5448717948717948

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[4-(prop-2-enoylamino)butanoyl]piperazine-1-carbonyl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C30H33ClN8O4

Similarity:  0.5345911949685535

Relative Targets:   Focal adhesion kinase 1  |

Name:  Rociletinib

Formula:  C27H28F3N7O3

Similarity:  0.5294117647058824

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.528169014084507

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.528169014084507

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.528169014084507

Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |

Name:  2-[[5-chloro-2-[4-[4-[5-(prop-2-enoylamino)pentanoyl]piperazine-1-carbonyl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C31H35ClN8O4

Similarity:  0.5246913580246914

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-[[5-chloro-2-[4-[1-[2-(prop-2-enoylamino)acetyl]-4-piperidyl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H30ClN7O3

Similarity:  0.5228758169934641

Relative Targets:   Focal adhesion kinase 1  |

Name:  [2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C24H25ClN6O2

Similarity:  0.5174825174825175

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |