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Approved Drugs
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Inhibitors
Name:  [2-[[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate
Formula:  C25H27ClN6O3
Similarity:  0.6386554621848739
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |
Name:  [2-[[5-Chloro-2-(3-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl] prop-2-enoate
Formula:  C23H22ClN5O3
Similarity:  0.6347826086956522
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-(2-chloro-6-methyl-phenyl)-2-(2-methoxy-4-morpholino-anilino)-4-[2-(prop-2-enoylamino)anilino]pyrimidine-5-carboxamide
Formula:  C32H32ClN7O4
Similarity:  0.625
Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |
Name:  [2-[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl] prop-2-enoate
Formula:  C23H22ClN5O3
Similarity:  0.6206896551724138
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H24ClN5O4
Similarity:  0.6083333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.5725806451612904
Relative Targets:   Epidermal growth factor receptor  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.5348837209302325
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  2-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]anilino]ethanesulfonyl fluoride
Formula:  C25H29ClFN7O4S
Similarity:  0.5298507462686567
Relative Targets:   Epidermal growth factor receptor  |
Name:  2-[[5-chloro-2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide
Formula:  C28H31ClN8O3
Similarity:  0.5294117647058824
Relative Targets:   Focal adhesion kinase 1  |
Name:  2-[[5-chloro-2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide
Formula:  C27H29ClN8O3
Similarity:  0.5259259259259259
Relative Targets:   Focal adhesion kinase 1  |
Name:  N-[3-[7-(2-methoxy-4-morpholino-anilino)-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C27H29N7O4
Similarity:  0.5223880597014925
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C30H35ClN8O4
Similarity:  0.5208333333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-(2-chloro-6-methyl-phenyl)-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-4-[2-(prop-2-enoylamino)anilino]pyrimidine-5-carboxamide
Formula:  C33H35ClN8O3
Similarity:  0.5170068027210885
Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |
Name:  2-[[5-chloro-2-[4-[4-[3-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide
Formula:  C28H31ClN8O3
Similarity:  0.5144927536231884
Relative Targets:   Focal adhesion kinase 1  |
Name:  [2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate
Formula:  C24H25ClN6O2
Similarity:  0.5079365079365079
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[[2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C25H27N7O4
Similarity:  0.5075757575757576
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-chloro-3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-phenyl]prop-2-enamide
Formula:  C25H26Cl2N6O3
Similarity:  0.5038167938931297
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.5038167938931297
Relative Targets:   Epidermal growth factor receptor  |
Name:  2-[[5-chloro-2-[[2-[2-(prop-2-enoylamino)acetyl]-3,4-dihydro-1H-isoquinolin-6-yl]amino]pyrimidin-4-yl]amino]-N-methyl-benzamide
Formula:  C26H26ClN7O3
Similarity:  0.5037593984962406
Relative Targets:   Focal adhesion kinase 1  |