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Approved Drugs
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Inhibitors
Name:  2-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]anilino]ethanesulfonyl fluoride
Formula:  C25H29ClFN7O4S
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  |
Name:  (4-fluorophenyl) 3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]benzoate
Formula:  C30H28ClFN6O4
Similarity:  0.6333333333333333
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.5306122448979592
Relative Targets:   Epidermal growth factor receptor  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.5302013422818792
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  Rociletinib
Formula:  C27H28F3N7O3
Similarity:  0.5192307692307693
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H31N7O4
Similarity:  0.5125
Relative Targets:   Tyrosine-protein kinase JAK3  |