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Approved Drugs
Inhibitors
Name:  [2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-4-[3-(prop-2-enoylamino)phenoxy]pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate
Formula:  C32H36N8O6
Similarity:  0.8740740740740741
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H28N8O2
Similarity:  0.7014925373134329
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C27H29N7O3
Similarity:  0.6382978723404256
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H26FN7O2
Similarity:  0.6285714285714286
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase ITK/TSK  |
Name:  N-[3-[[2-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H26ClN7O2
Similarity:  0.6285714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H26N8O4
Similarity:  0.6180555555555556
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C26H27N7O2
Similarity:  0.5694444444444444
Relative Targets:   Epidermal growth factor receptor  |
Name:  Olmutinib
Formula:  C26H26N6O2S
Similarity:  0.547945205479452
Relative Targets:   Tyrosine-protein kinase BTK  |
Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide
Formula:  C25H26N8O2
Similarity:  0.547945205479452
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.5422535211267606
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.5422535211267606
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.527027027027027
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.5238095238095238
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O3
Similarity:  0.5234899328859061
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.5135135135135135
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H27ClN6O2
Similarity:  0.5102040816326531
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H26N6O2
Similarity:  0.5069444444444444
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-(dimethylamino)-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C28H34N6O3
Similarity:  0.506578947368421
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.5033557046979866
Relative Targets:   Dipeptidyl peptidase 1  |