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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.6201550387596899

Inhibitors

Name:  N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26FN7O2

Similarity:  0.8672566371681416

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[[2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.8672566371681416

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26ClN7O2

Similarity:  0.8672566371681416

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26N8O4

Similarity:  0.8305084745762712

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.7863247863247863

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.672

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.672

Relative Targets:   Epidermal growth factor receptor  |

Name:  [2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-4-[3-(prop-2-enoylamino)phenoxy]pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate

Formula:  C32H38N8O4

Similarity:  0.6382978723404256

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.6299212598425197

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.6201550387596899

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6171875

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  [2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-4-[3-(prop-2-enoylamino)phenoxy]pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate

Formula:  C32H36N8O6

Similarity:  0.6164383561643836

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.616

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.616

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.6068376068376068

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-cyano-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C27H28N6O3

Similarity:  0.6030534351145038

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-ethynyl-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H29N5O3

Similarity:  0.6030534351145038

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C28H32N8O3

Similarity:  0.6029411764705882

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-pyrrolidin-1-yl-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C30H36N6O3

Similarity:  0.5942028985507246

Relative Targets:   Dipeptidyl peptidase 1  |