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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.6106870229007634

Inhibitors

Name:  N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26FN7O2

Similarity:  0.8521739130434782

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[[2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.8521739130434782

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26ClN7O2

Similarity:  0.8521739130434782

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C27H29N7O3

Similarity:  0.8305084745762712

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.773109243697479

Relative Targets:   Epidermal growth factor receptor  |

Name:  [2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-4-[3-(prop-2-enoylamino)phenoxy]pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate

Formula:  C32H36N8O6

Similarity:  0.7122302158273381

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.6614173228346457

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.6614173228346457

Relative Targets:   Epidermal growth factor receptor  |

Name:  [2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-4-[3-(prop-2-enoylamino)phenoxy]pyrrolo[2,3-d]pyrimidin-7-yl]methyl 2,2-dimethylpropanoate

Formula:  C32H38N8O4

Similarity:  0.6180555555555556

Relative Targets:   Epidermal growth factor receptor  |

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.6106870229007634

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6062992125984252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.6062992125984252

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.5966386554621849

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-3-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.5833333333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.5746268656716418

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.5658914728682171

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.5597014925373134

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.5572519083969466

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.556390977443609

Relative Targets:   Epidermal growth factor receptor  |