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Approved Drugs
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Inhibitors
Name:  5-[[3-[(2-chloroacetyl)amino]phenyl]methylamino]-7-[4-(4-methylpiperazin-1-yl)anilino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C27H30ClN9O2
Similarity:  0.8347107438016529
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  5-[[3-[(2-chloroacetyl)amino]phenyl]methylamino]-7-[4-(4-methyl-1,4-diazepan-1-yl)anilino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C28H32ClN9O2
Similarity:  0.8145161290322581
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  5-[[3-[(2-chloroacetyl)amino]phenyl]methylamino]-7-[4-(dimethylamino)anilino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C24H25ClN8O2
Similarity:  0.7272727272727273
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  5-[[3-[(2-chloroacetyl)amino]phenyl]methylamino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C24H24ClN7O4
Similarity:  0.6060606060606061
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.5846153846153846
Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |
Name:  5-[[4-[(2-chloroacetyl)amino]phenyl]methylamino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C24H24ClN7O4
Similarity:  0.5703703703703704
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  7-(3,5-dimethoxyanilino)-5-[[3-(propanoylamino)phenyl]methylamino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C25H27N7O4
Similarity:  0.5474452554744526
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  2-cyano-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide
Formula:  C23H22N6O2
Similarity:  0.5227272727272727
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide
Formula:  C25H26N6O3
Similarity:  0.5144927536231884
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide
Formula:  C25H25N7O3
Similarity:  0.5142857142857142
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  7-(3,5-dimethoxyanilino)-5-[[3-(prop-2-enoylamino)phenyl]methylamino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C25H25N7O4
Similarity:  0.5142857142857142
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  7-(3,5-dimethoxyanilino)-5-[[3-(prop-2-ynoylamino)phenyl]methylamino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C25H23N7O4
Similarity:  0.5142857142857142
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  7-(3,5-dimethoxyanilino)-5-[[3-(2-methylprop-2-enoylamino)phenyl]methylamino]imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C26H27N7O4
Similarity:  0.5070422535211268
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C24H25N7O3
Similarity:  0.5035971223021583
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide
Formula:  C26H28N6O3
Similarity:  0.5035460992907801
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  5-[[3-(but-2-ynoylamino)phenyl]methylamino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide
Formula:  C26H25N7O4
Similarity:  0.5034965034965035
Relative Targets:   Tyrosine-protein kinase ZAP-70  |
Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C23H23N5O2
Similarity:  0.5
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide
Formula:  C23H22N6O2
Similarity:  0.5
Relative Targets:   Tyrosine-protein kinase JAK3  |