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Approved Drugs
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Inhibitors
Name: N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-hydroxypropoxy)phenyl]prop-2-enamide
Formula: C30H27ClN6O4
Similarity: 0.9421487603305785
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Formula: C31H30ClN7O3
Similarity: 0.8809523809523809
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-methoxy-1-methyl-ethoxy)phenyl]prop-2-enamide
Formula: C31H29ClN6O4
Similarity: 0.8091603053435115
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula: C27H21ClN6O2
Similarity: 0.768
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula: C31H27N7O3
Similarity: 0.6737588652482269
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[4-[(2-benzyl-1H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula: C31H27N7O3
Similarity: 0.6737588652482269
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula: C28H21ClFN5O2
Similarity: 0.6277372262773723
Relative Targets: Epidermal growth factor receptor |
Name: N-[5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula: C32H26N6O5
Similarity: 0.6216216216216216
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula: C25H20ClN5O2
Similarity: 0.6060606060606061
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClN5O4
Similarity: 0.5664335664335665
Relative Targets: Epidermal growth factor receptor |
Name: N-[2-[2-(dimethylamino)ethoxy]-5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula: C34H31N7O4
Similarity: 0.5506329113924051
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C29H31ClN6O4
Similarity: 0.54
Relative Targets: Epidermal growth factor receptor |
Name: N-[[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]isoxazol-3-yl]methyl]prop-2-enamide
Formula: C23H19ClN6O3
Similarity: 0.5251798561151079
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula: C38H35ClN8O2
Similarity: 0.5235294117647059
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClFN4O4
Similarity: 0.5205479452054794
Relative Targets: Epidermal growth factor receptor |
Name: N-[[2-[4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula: C23H20ClN7O3
Similarity: 0.5177304964539007
Relative Targets: Aurora kinase A | Tyrosine-protein kinase JAK2 | Tyrosine-protein kinase ABL1 | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Insulin receptor | Insulin-like growth factor 1 receptor | Hepatocyte growth factor receptor | Platelet-derived growth factor receptor beta | Mast/stem cell growth factor receptor Kit | Fibroblast growth factor receptor 1 | Platelet-derived growth factor receptor alpha | Vascular endothelial growth factor receptor 1 | Receptor-type tyrosine-protein kinase FLT3 | Tyrosine-protein kinase Blk | Dual specificity mitogen-activated protein kinase kinase 1 | Focal adhesion kinase 1 | Receptor tyrosine-protein kinase erbB-4 |
Name: N-[[2-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula: C23H19ClN6O3
Similarity: 0.5142857142857142
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (Z)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5133333333333333
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5133333333333333
Relative Targets: Epidermal growth factor receptor |