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Approved Drugs
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Inhibitors
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C29H25ClN6O4
Similarity:  0.8091603053435115
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Formula:  C31H30ClN7O3
Similarity:  0.8059701492537313
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-hydroxypropoxy)phenyl]prop-2-enamide
Formula:  C30H27ClN6O4
Similarity:  0.7910447761194029
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21ClN6O2
Similarity:  0.7384615384615385
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C28H21ClFN5O2
Similarity:  0.6056338028169014
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C25H20ClN5O2
Similarity:  0.583941605839416
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C31H27N7O3
Similarity:  0.5548387096774193
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[(2-benzyl-1H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C31H27N7O3
Similarity:  0.5548387096774193
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClN5O4
Similarity:  0.5472972972972973
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C29H31ClN6O4
Similarity:  0.5324675324675324
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C38H35ClN8O2
Similarity:  0.5172413793103449
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethoxy]-5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C34H31N7O4
Similarity:  0.5151515151515151
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C32H26N6O5
Similarity:  0.5123456790123457
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]isoxazol-3-yl]methyl]prop-2-enamide
Formula:  C23H19ClN6O3
Similarity:  0.5069444444444444
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula:  C27H24ClFN4O4
Similarity:  0.5033112582781457
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[[2-[4-amino-6-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]oxazol-4-yl]methyl]prop-2-enamide
Formula:  C23H20ClN7O3
Similarity:  0.5
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK2  | Tyrosine-protein kinase ABL1  | Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Insulin receptor  | Insulin-like growth factor 1 receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor beta  | Mast/stem cell growth factor receptor Kit  | Fibroblast growth factor receptor 1  | Platelet-derived growth factor receptor alpha  | Vascular endothelial growth factor receptor 1  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Dual specificity mitogen-activated protein kinase kinase 1  | Focal adhesion kinase 1  | Receptor tyrosine-protein kinase erbB-4  |