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Approved Drugs
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Inhibitors
Name:  N-[3-[4-[(1-benzylindol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C30H24N6O
Similarity:  0.8319327731092437
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C31H27N7O3
Similarity:  0.7751937984496124
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-(4-benzylanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C28H23N5O
Similarity:  0.7416666666666667
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[(2-benzyl-1H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C29H23N7O
Similarity:  0.7301587301587301
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-(4-phenoxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21N5O2
Similarity:  0.6854838709677419
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C30H22N6O3
Similarity:  0.6567164179104478
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C27H21ClN6O2
Similarity:  0.6461538461538462
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C28H21ClFN5O2
Similarity:  0.6363636363636364
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C30H22N6O4
Similarity:  0.6071428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[4-(4-benzhydryloxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C34H27N5O2
Similarity:  0.5972222222222222
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[(2-benzyl-1H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C31H27N7O3
Similarity:  0.5684931506849316
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C27H26N8O
Similarity:  0.5285714285714286
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]pyrimidin-5-yl]phenyl]prop-2-enamide
Formula:  C25H20ClN5O2
Similarity:  0.5185185185185185
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  N-[4-[[5-(3-quinolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C24H17N5O2
Similarity:  0.5151515151515151
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C32H26N6O5
Similarity:  0.512987012987013
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31N7O2
Similarity:  0.5102040816326531
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula:  C29H28N8O
Similarity:  0.5
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[5-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Formula:  C29H25ClN6O4
Similarity:  0.5
Relative Targets:   Epidermal growth factor receptor  |