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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5241379310344828

Inhibitors

Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C39H35ClFN7O2

Similarity:  0.7254901960784313

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C38H35ClN8O2

Similarity:  0.7236842105263158

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O3

Similarity:  0.7197452229299363

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.71875

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O4

Similarity:  0.70625

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.7022900763358778

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isopropoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.6917293233082706

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-benzhydryloxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C45H41N7O2

Similarity:  0.6848484848484848

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isobutoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.6764705882352942

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.6590909090909091

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-ethyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.6444444444444445

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.635036496350365

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-[4-[[2-(1-oxoisoindolin-2-yl)-2-phenyl-acetyl]amino]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C48H43N9O3

Similarity:  0.6243093922651933

Relative Targets:   Epidermal growth factor receptor  |

Name:  [4-[[6-[4-(4-methylpiperazin-1-yl)phenyl]-5-[3-(prop-2-enoylamino)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]phenyl] 2-(1-oxoisoindolin-2-yl)-2-phenyl-acetate

Formula:  C48H42N8O4

Similarity:  0.6243093922651933

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isobutyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.6214285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.5474452554744526

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.5454545454545454

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.539568345323741

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.5374149659863946

Relative Targets:   Tyrosine-protein kinase JAK3  |