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Inhibitors

Name:  [4-[[6-[4-(4-methylpiperazin-1-yl)phenyl]-5-[3-(prop-2-enoylamino)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]phenyl] 2-(1-oxoisoindolin-2-yl)-2-phenyl-acetate

Formula:  C48H42N8O4

Similarity:  0.776595744680851

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-[4-[[2-(1-oxoisoindolin-2-yl)-2-phenyl-acetyl]amino]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C48H43N9O3

Similarity:  0.7395833333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O4

Similarity:  0.7010869565217391

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-hydroxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C32H31N7O2

Similarity:  0.6848484848484848

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O3

Similarity:  0.6756756756756757

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-benzhydryloxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C34H27N5O2

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C38H35ClN8O2

Similarity:  0.6502732240437158

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C39H35ClFN7O2

Similarity:  0.6344086021505376

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isopropoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5588235294117647

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.5568862275449101

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C36H35N7O2

Similarity:  0.5478723404255319

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.5470588235294118

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isobutoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.5402298850574713

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[4-(4-methylpiperazin-1-yl)anilino]-N-(4-phenoxyphenyl)-4-[2-(prop-2-enoylamino)anilino]pyrimidine-5-carboxamide

Formula:  C37H36N8O3

Similarity:  0.51010101010101

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[[2-[4-(4-methylpiperazin-1-yl)anilino]-5-[(4-phenoxyphenyl)methoxy]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C37H37N7O3

Similarity:  0.5076142131979695

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.5058139534883721

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5

Relative Targets:   Epidermal growth factor receptor  |