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Inhibitors

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O4

Similarity:  0.8944099378881988

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-hydroxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C32H31N7O2

Similarity:  0.7197452229299363

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-[4-[[2-(1-oxoisoindolin-2-yl)-2-phenyl-acetyl]amino]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C48H43N9O3

Similarity:  0.6979166666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  [4-[[6-[4-(4-methylpiperazin-1-yl)phenyl]-5-[3-(prop-2-enoylamino)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]phenyl] 2-(1-oxoisoindolin-2-yl)-2-phenyl-acetate

Formula:  C48H42N8O4

Similarity:  0.6979166666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C39H35ClFN7O2

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C38H35ClN8O2

Similarity:  0.68

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-benzhydryloxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C45H41N7O2

Similarity:  0.6756756756756757

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H22N6O3

Similarity:  0.65

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.575

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.5740740740740741

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H22N6O4

Similarity:  0.5705882352941176

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.5590062111801242

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-ethyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.558282208588957

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isopropoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5575757575757576

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isobutoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.5568862275449101

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide

Formula:  C32H26N6O5

Similarity:  0.5449438202247191

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5421686746987951

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isobutyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.5416666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethoxy]-5-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C34H31N7O4

Similarity:  0.5384615384615384

Relative Targets:   Epidermal growth factor receptor  |