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Approved Drugs

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Inhibitors

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C38H35ClN8O2

Similarity:  0.8343949044585988

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-hydroxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C32H31N7O2

Similarity:  0.7254901960784313

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O3

Similarity:  0.6818181818181818

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O4

Similarity:  0.6797752808988764

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H21ClFN5O2

Similarity:  0.6363636363636364

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-benzhydryloxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C45H41N7O2

Similarity:  0.6344086021505376

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.6168831168831169

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.6078431372549019

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isobutoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.5974842767295597

Relative Targets:   Epidermal growth factor receptor  |

Name:  [4-[[6-[4-(4-methylpiperazin-1-yl)phenyl]-5-[3-(prop-2-enoylamino)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]phenyl] 2-(1-oxoisoindolin-2-yl)-2-phenyl-acetate

Formula:  C48H42N8O4

Similarity:  0.5920398009950248

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isopropoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5886075949367089

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-[4-[[2-(1-oxoisoindolin-2-yl)-2-phenyl-acetyl]amino]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C48H43N9O3

Similarity:  0.5841584158415841

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.5506329113924051

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-ethyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.55

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.5337423312883436

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isobutyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.5333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-amino-3-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H20ClFN6O2

Similarity:  0.5120481927710844

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H21ClN6O2

Similarity:  0.5060240963855421

Relative Targets:   Epidermal growth factor receptor  |