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Approved Drugs

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Inhibitors

Name:  N-[3-[3-ethyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.8839285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-isopropyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.868421052631579

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.8407079646017699

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isobutoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C30H34N6O2

Similarity:  0.7642276422764228

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-isopropoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C29H32N6O2

Similarity:  0.7540983606557377

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C27H28N6O2

Similarity:  0.7272727272727273

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C28H30N6O2

Similarity:  0.7235772357723578

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-(4-hydroxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C32H31N7O2

Similarity:  0.6214285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methyl]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O3

Similarity:  0.5416666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C38H35ClN8O2

Similarity:  0.5398773006134969

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C39H35ClFN7O2

Similarity:  0.5333333333333333

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[4-[4-[(1,3-dioxoisoindolin-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide

Formula:  C41H36N8O4

Similarity:  0.5321637426900585

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C31H35N7O3

Similarity:  0.5100671140939598

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[3-methyl-7-[4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C27H30N8O2

Similarity:  0.5070422535211268

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.5035460992907801

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.5034965034965035

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.5

Relative Targets:   Epidermal growth factor receptor  |