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Approved Drugs

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Inhibitors

Name:  2-cyano-N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.8383838383838383

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.8080808080808081

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.7843137254901961

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.7843137254901961

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C25H25N7O3

Similarity:  0.6929824561403509

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.6851851851851852

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6728971962616822

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6545454545454545

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6272727272727273

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6106194690265486

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C24H25N7O3

Similarity:  0.6101694915254238

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C25H26N6O3

Similarity:  0.6101694915254238

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C26H28N6O3

Similarity:  0.5950413223140496

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.5714285714285714

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-methylsulfanyl-2-(4-morpholinoanilino)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26N6O2S

Similarity:  0.5583333333333333

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.5491803278688525

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.544

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.5431034482758621

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.5333333333333333

Relative Targets:   Dipeptidyl peptidase 1  |