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Approved Drugs

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Inhibitors

Name:  2-cyano-N-[2-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C19H18N8O2

Similarity:  0.7878787878787878

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H19N7O2

Similarity:  0.7058823529411765

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C18H17N7O2

Similarity:  0.6862745098039216

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H21N7O2

Similarity:  0.6857142857142857

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.6826923076923077

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C17H15N7O

Similarity:  0.66

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C21H23N7O3

Similarity:  0.6486486486486487

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C22H25N7O3

Similarity:  0.631578947368421

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C25H25N7O3

Similarity:  0.568

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.5625

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C18H18N6O2

Similarity:  0.5504587155963303

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5495495495495496

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5495495495495496

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C20H23N7O

Similarity:  0.5398230088495575

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.5350877192982456

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C21H25N7O

Similarity:  0.5258620689655172

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C17H16N6O

Similarity:  0.5233644859813084

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C18H18N6O

Similarity:  0.509090909090909

Relative Targets:   Tyrosine-protein kinase JAK3  |