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Approved Drugs

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Inhibitors

Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H19N7O2

Similarity:  0.8522727272727273

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C19H20N6O2

Similarity:  0.7692307692307693

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.7634408602150538

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C18H18N6O

Similarity:  0.7613636363636364

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C21H25N7O

Similarity:  0.7473684210526316

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C22H25N7O3

Similarity:  0.7326732673267327

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C21H21N9O3

Similarity:  0.6857142857142857

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C20H23N7O

Similarity:  0.6464646464646465

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C18H18N6O2

Similarity:  0.6458333333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.6428571428571429

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C21H23N7O3

Similarity:  0.638095238095238

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C17H16N6O

Similarity:  0.6344086021505376

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.6237623762376238

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C17H15N7O

Similarity:  0.5979381443298969

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C19H18N8O2

Similarity:  0.5961538461538461

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C18H17N7O2

Similarity:  0.594059405940594

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.5922330097087378

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C26H28N6O3

Similarity:  0.5289256198347108

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.5263157894736842

Relative Targets:   Tyrosine-protein kinase JAK3  |