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Approved Drugs

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Inhibitors

Name:  2-cyano-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C25H25N7O3

Similarity:  0.8737864077669902

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.8383838383838383

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.8080808080808081

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.7843137254901961

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.7843137254901961

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C25H26N6O3

Similarity:  0.7757009345794392

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C26H28N6O3

Similarity:  0.7545454545454545

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6728971962616822

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6545454545454545

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.6545454545454545

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6272727272727273

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6106194690265486

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C17H15N7O

Similarity:  0.5825242718446602

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C18H17N7O2

Similarity:  0.5504587155963303

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.5357142857142857

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.5333333333333333

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.5203252032520326

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C24H25N7O3

Similarity:  0.52

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.5169491525423728

Relative Targets:   Tyrosine-protein kinase JAK3  |