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Approved Drugs
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Inhibitors
Name: (E)-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula: C20H22N6O2
Similarity: 0.8488372093023255
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C19H20N6O2
Similarity: 0.813953488372093
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: 2-cyano-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula: C19H19N7O2
Similarity: 0.7865168539325843
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C19H20N6O2
Similarity: 0.7528089887640449
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula: C20H22N6O2
Similarity: 0.6914893617021277
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide
Formula: C21H23N7O3
Similarity: 0.6868686868686869
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C18H18N6O2
Similarity: 0.6813186813186813
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C20H23N7O
Similarity: 0.6631578947368421
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C19H20N6O2
Similarity: 0.6421052631578947
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: 2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula: C19H19N7O2
Similarity: 0.6391752577319587
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: (E)-N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula: C20H22N6O2
Similarity: 0.6391752577319587
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C17H16N6O
Similarity: 0.6153846153846154
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula: C19H19N7O2
Similarity: 0.6122448979591837
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide
Formula: C22H25N7O3
Similarity: 0.6037735849056604
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula: C19H20N6O2
Similarity: 0.5918367346938775
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: 2-cyano-N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula: C19H19N7O2
Similarity: 0.59
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula: C21H25N7O
Similarity: 0.5631067961165048
Relative Targets: Tyrosine-protein kinase JAK3 |
Name: N-[3-[[[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula: C20H22ClN7O2
Similarity: 0.5327102803738317
Relative Targets: Aurora kinase A | Tyrosine-protein kinase JAK1 | Non-receptor tyrosine-protein kinase TYK2 | Dual specificity protein kinase TTK | Receptor-type tyrosine-protein kinase FLT3 | Tyrosine-protein kinase JAK3 |
Name: N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula: C23H23N7O3
Similarity: 0.5309734513274337
Relative Targets: Tyrosine-protein kinase JAK3 |