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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.532258064516129

Inhibitors

Name:  (E)-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.8645833333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.8333333333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.8080808080808081

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.7777777777777778

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C24H25N7O3

Similarity:  0.7476635514018691

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.7211538461538461

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6880733944954128

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-methylsulfanyl-2-(4-morpholinoanilino)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26N6O2S

Similarity:  0.6880733944954128

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6761904761904762

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.6756756756756757

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  (E)-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C24H25N5O2

Similarity:  0.6728971962616822

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.6728971962616822

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C25H26N6O3

Similarity:  0.6696428571428571

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.6605504587155964

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.6454545454545455

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-cyano-N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]acetamide

Formula:  C23H22N6O2

Similarity:  0.6272727272727273

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-(4-morpholinoanilino)-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C25H23N7O3

Similarity:  0.6101694915254238

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-(cyclopropylmethyl)-2-(4-morpholinoanilino)-8-oxo-purin-9-yl]phenyl]prop-2-enamide

Formula:  C28H29N7O3

Similarity:  0.6097560975609756

Relative Targets:   Tyrosine-protein kinase BTK  |