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Approved Drugs
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Inhibitors
Name:  N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.813953488372093
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.7528089887640449
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C20H22N6O2
Similarity:  0.6914893617021277
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C20H22ClN7O2
Similarity:  0.6565656565656566
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase JAK3  |
Name:  N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.6421052631578947
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C20H22N6O2
Similarity:  0.6391752577319587
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula:  C19H19N7O2
Similarity:  0.6391752577319587
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide
Formula:  C21H23N7O3
Similarity:  0.6372549019607843
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C23H23N7O3
Similarity:  0.6320754716981132
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C18H18N6O2
Similarity:  0.6276595744680851
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C20H23N7O
Similarity:  0.6122448979591837
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula:  C19H19N7O2
Similarity:  0.59
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[2-[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C19H19ClN6O3
Similarity:  0.5784313725490197
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[5-chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C19H19ClN6O3
Similarity:  0.5784313725490197
Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |
Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H19N7O2
Similarity:  0.5643564356435643
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C17H16N6O
Similarity:  0.5638297872340425
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide
Formula:  C22H25N7O3
Similarity:  0.5596330275229358
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[[5-Chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C19H20ClN7O2
Similarity:  0.5480769230769231
Relative Targets:   Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C19H20N6O2
Similarity:  0.5445544554455446
Relative Targets:   Tyrosine-protein kinase JAK3  |