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Inhibitors

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.8433734939759037

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C19H20N6O2

Similarity:  0.8433734939759037

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C20H23N7O

Similarity:  0.8235294117647058

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C18H17N7O2

Similarity:  0.7790697674418605

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C17H16N6O

Similarity:  0.7777777777777778

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H19N7O2

Similarity:  0.7613636363636364

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.7142857142857143

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C21H23N7O3

Similarity:  0.7083333333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C21H25N7O

Similarity:  0.6989247311827957

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.6813186813186813

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.6595744680851063

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C18H18N6O

Similarity:  0.651685393258427

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H21N7O2

Similarity:  0.6458333333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.6276595744680851

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C22H25N7O3

Similarity:  0.6213592233009708

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C17H15N7O

Similarity:  0.6153846153846154

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[[5-Chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C19H20ClN7O2

Similarity:  0.58

Relative Targets:   Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.5757575757575758

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C19H18N8O2

Similarity:  0.5643564356435643

Relative Targets:   Tyrosine-protein kinase JAK3  |