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Approved Drugs
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Inhibitors
Name:  (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C21H25N7O
Similarity:  0.8522727272727273
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C18H18N6O2
Similarity:  0.8235294117647058
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.8160919540229885
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C17H16N6O
Similarity:  0.7529411764705882
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H19N7O2
Similarity:  0.7391304347826086
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C19H20N6O2
Similarity:  0.717391304347826
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C20H22N6O2
Similarity:  0.7127659574468085
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide
Formula:  C21H23N7O3
Similarity:  0.69
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.6631578947368421
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C18H18N6O
Similarity:  0.6521739130434783
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C20H21N7O2
Similarity:  0.6464646464646465
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula:  C18H17N7O2
Similarity:  0.6458333333333334
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide
Formula:  C19H19N7O2
Similarity:  0.6428571428571429
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide
Formula:  C22H25N7O3
Similarity:  0.6226415094339622
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.6122448979591837
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide
Formula:  C17H15N7O
Similarity:  0.6
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C24H26N8O2
Similarity:  0.5855855855855856
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide
Formula:  C20H22N6O2
Similarity:  0.5784313725490197
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C22H24N8O2
Similarity:  0.5779816513761468
Relative Targets:   Epidermal growth factor receptor  |