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Inhibitors

Name:  (E)-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C18H18N6O

Similarity:  0.8311688311688312

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C18H18N6O2

Similarity:  0.7777777777777778

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.7710843373493976

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C17H15N7O

Similarity:  0.7625

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C20H23N7O

Similarity:  0.7529411764705882

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H19N7O2

Similarity:  0.7529411764705882

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C19H20N6O2

Similarity:  0.6704545454545454

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[2-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]acetamide

Formula:  C19H18N8O2

Similarity:  0.6703296703296703

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H22N6O2

Similarity:  0.6483516483516484

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]prop-2-enamide

Formula:  C21H23N7O3

Similarity:  0.6458333333333334

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C21H25N7O

Similarity:  0.6344086021505376

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[3-[6-[[1-[2-(methylamino)-2-oxo-ethyl]pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]but-2-enamide

Formula:  C20H21N7O2

Similarity:  0.6344086021505376

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.6153846153846154

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C18H17N7O2

Similarity:  0.5978260869565217

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-cyano-N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]acetamide

Formula:  C19H19N7O2

Similarity:  0.5957446808510638

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.57

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5638297872340425

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  (E)-N-[2-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]anilino]-2-oxo-ethyl]but-2-enamide

Formula:  C22H25N7O3

Similarity:  0.5631067961165048

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[[5-Chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C18H18ClN7O

Similarity:  0.5531914893617021

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |