Searching results

Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5853658536585366

Inhibitors

Name:  N-[3-[[3-chloro-6-(4-piperazin-1-ylanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H24ClN5O2

Similarity:  0.8235294117647058

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.8076923076923077

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H30ClN5O2

Similarity:  0.7433628318584071

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopentylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C30H34ClN5O2

Similarity:  0.7

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[6-[4-(2-aminoethyl)anilino]-3-chloro-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C22H21ClN4O2

Similarity:  0.6761904761904762

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6605504587155964

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6605504587155964

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6491228070175439

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6434782608695652

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-(4-morpholinoanilino)-5-(4-pyridyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C30H27N7O3

Similarity:  0.6356589147286822

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H24ClN5O4

Similarity:  0.6324786324786325

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6306306306306306

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6218487394957983

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[6-[3-(aminomethyl)anilino]-3-chloro-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C21H19ClN4O2

Similarity:  0.616822429906542

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[2-(4-morpholinoanilino)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C24H25N7O3

Similarity:  0.6134453781512605

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.6017699115044248

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[5-methylsulfanyl-2-(4-morpholinoanilino)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26N6O2S

Similarity:  0.6016949152542372

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.5932203389830508

Relative Targets:   Epidermal growth factor receptor  |

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.5916666666666667

Relative Targets:   Tyrosine-protein kinase BTK  |