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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5853658536585366

Inhibitors

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.8235294117647058

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.8076923076923077

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H30ClN5O2

Similarity:  0.7433628318584071

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopentylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C30H34ClN5O2

Similarity:  0.7

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[6-[4-(2-aminoethyl)anilino]-3-chloro-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C22H21ClN4O2

Similarity:  0.6761904761904762

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6491228070175439

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.6218487394957983

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[6-[3-(aminomethyl)anilino]-3-chloro-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C21H19ClN4O2

Similarity:  0.616822429906542

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.5983606557377049

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.5932203389830508

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.5897435897435898

Relative Targets:   Epidermal growth factor receptor  |

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5853658536585366

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.5725806451612904

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.56

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.5528455284552846

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.544

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-(4-morpholinoanilino)-5-(4-pyridyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C30H27N7O3

Similarity:  0.5401459854014599

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H29ClN6O2

Similarity:  0.5396825396825397

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.5338983050847458

Relative Targets:   Tyrosine-protein kinase JAK3  |