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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.7280701754385965

Inhibitors

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.8095238095238095

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H30ClN5O2

Similarity:  0.8090909090909091

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-(4-piperazin-1-ylanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H24ClN5O2

Similarity:  0.8076923076923077

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-(4-morpholinoanilino)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C24H23ClN4O3

Similarity:  0.8076923076923077

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.7727272727272727

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-chloro-6-[4-[4-(cyclopentylmethyl)piperazin-1-yl]anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C30H34ClN5O2

Similarity:  0.7606837606837606

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.7431192660550459

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.7407407407407407

Relative Targets:   Epidermal growth factor receptor  |

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.7280701754385965

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.7280701754385965

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.6982758620689655

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.6982758620689655

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-cyano-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C27H28N6O3

Similarity:  0.6638655462184874

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-ethynyl-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H29N5O3

Similarity:  0.6638655462184874

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.6637931034482759

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[6-[4-(2-aminoethyl)anilino]-3-chloro-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C22H21ClN4O2

Similarity:  0.6635514018691588

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[[3-(dimethylamino)-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C28H34N6O3

Similarity:  0.6528925619834711

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.652542372881356

Relative Targets:   Epidermal growth factor receptor  |