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Approved Drugs
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Inhibitors
Name: 1-[4-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C29H33N9O3
Similarity: 0.8604651162790697
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C30H34N8O3
Similarity: 0.8320610687022901
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C30H34N8O3
Similarity: 0.7910447761194029
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[(3R)-3-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C29H33N9O3
Similarity: 0.7518248175182481
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C31H36N10O3
Similarity: 0.7034482758620689
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C33H38N10O2
Similarity: 0.6845637583892618
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[2-(4-morpholinoanilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula: C24H27N5O3S
Similarity: 0.6439393939393939
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(3R)-3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C31H38N10O2
Similarity: 0.6333333333333333
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[(3R)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C31H36N10O3
Similarity: 0.625
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[(3S)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C31H36N10O3
Similarity: 0.625
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one
Formula: C25H31N7O2
Similarity: 0.5869565217391305
Relative Targets: Epidermal growth factor receptor |
Name: 1-[(2S)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C31H36N10O3
Similarity: 0.5632911392405063
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[(2R)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one
Formula: C31H36N10O3
Similarity: 0.5632911392405063
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula: C25H30N6O2S
Similarity: 0.5422535211267606
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[2-(4-morpholinoanilino)-5-(4-pyridyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula: C30H27N7O3
Similarity: 0.535483870967742
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula: C32H32N10O3
Similarity: 0.5337423312883436
Relative Targets: Tyrosine-protein kinase ITK/TSK |
Name: 1-[4-[2-(2-methoxy-4-morpholino-anilino)thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula: C25H29N5O4S
Similarity: 0.5310344827586206
Relative Targets: Epidermal growth factor receptor |
Name: 1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one
Formula: C23H29ClN6O2
Similarity: 0.5142857142857142
Relative Targets: Epidermal growth factor receptor |