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Name:  1-[(3R)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.8814814814814815

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3S)-3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.8814814814814815

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-but-3-ynylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₃H₃₈N₁₀O₂

Similarity:  0.8169014084507042

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₂₉H₃₃N₉O₃

Similarity:  0.8161764705882353

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(2S)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.7887323943661971

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(2R)-2-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

Formula:  C₃₁H₃₆N₁₀O₃

Similarity:  0.7887323943661971

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₁H₃₈N₁₀O₂

Similarity:  0.7622377622377622

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[(3R)-3-[[5-[6-(methylamino)pyrazin-2-yl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₂₉H₃₃N₉O₃

Similarity:  0.7152777777777778

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[6-(methylamino)-2-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.7034482758620689

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[5-(methylamino)-3-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.6802721088435374

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)anilino]-5-[6-(methylamino)pyrazin-2-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C₃₂H₃₂N₁₀O₃

Similarity:  0.6688311688311688

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[5-[2-(methylamino)-4-pyridyl]-2-(4-morpholinoanilino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C₃₀H₃₄N₈O₃

Similarity:  0.6577181208053692

Relative Targets:   Tyrosine-protein kinase ITK/TSK  |

Name:  1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H31N7O2

Similarity:  0.6028368794326241

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C27H33N7O4

Similarity:  0.5945945945945946

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C25H30N6O2S

Similarity:  0.5586206896551724

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C23H29ClN6O2

Similarity:  0.5531914893617021

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]thieno[3,2-d]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C27H32N6O4S

Similarity:  0.5526315789473685

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[5-chloro-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]oxy-1-piperidyl]prop-2-en-1-one

Formula:  C24H31ClN6O3

Similarity:  0.5202702702702703

Relative Targets:   Epidermal growth factor receptor  |

Name:  1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-1-piperidyl]prop-2-en-1-one

Formula:  C25H30FN7O2

Similarity:  0.5099337748344371

Relative Targets:   Epidermal growth factor receptor  |